Holders Liverpool will take on Atletico Madrid, Manchester City face Real Madrid, Chelsea draw Bayern Munich in a repeat of the 2012 final and Tottenham face RB Leipzig in the last 16 of the Champions League.
Arguably the pick of the round is Manchester City’s tie with Real Madrid as former Barcelona manager Pep Guardiola faces his old foes.
Five-time winners Barcelona take on Napoli, Borussia Dortmund will play Paris St Germain and Italian champions Juventus face Lyon.
Italian club Atalanta, who qualified for the competition for the first time, will take on Valencia.
Chelsea have been drawn to play Bayern Munich and last season’s beaten finalists Tottenham will play current Bundesliga leaders RB Leipzig.
The first legs will be played on February 18-19 and February 25-26, with the second legs on March 10-11 and March 17-18.
Borussia Dortmund v Paris Saint-Germain
Real Madrid v Manchester City
Atalanta v Valencia
Atletico Madrid v Liverpool
Chelsea v Bayern Munich
Lyon v Juventus
Tottenham v RB Leipzig
Napoli v Barcelona
Champions League Knockout Stage – The Key Dates
February 18/19 & 25/26: Round of 16 – first leg
March 10/11 & 17/18: Round of 16 – second leg
April 7/8: Quarter-finals – first leg
April 14/15: Quarter-finals – second leg
April 28/29: Semi-finals – first leg
By Gerald Dandah